Quantitative Biology of Endocytosis
- Quantitative Cell Biology
- Categories:Biological Sciences
- Language:English(Translation Services Available)
- Publication date:July,2018
- Pages:88
- Retail Price:(Unknown)
- Size:190mm×234mm
- Page Views:253
- Words:(Unknown)
- Star Ratings:
- Text Color:Black and white
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Description
Author
Julien Berro, Ph.D., is an assistant professor of Molecular Biophysics and Biochemistry, and of Cell Biology at Yale University. He initially trained in Physics, Applied Mathematics and Computer Sciences at the Institut National Polytechnique of Grenoble, France. He obtained his Ph.D. in Mathematical Modeling in Biology at Universite Joseph Fourier, Grenoble, France, where he worked with Jean-Louis Martiel and Laurent Blanchoin on mathematical models for actin filament biochemistry and mechanics. After a brief tenure as an assistant professor in the department of Mathematics at Universite Claude Bernard, Lyon, France, he decided to further his training by learning cell biology and quantitative microscopy in the laboratory of Tom Pollard at Yale University. Since he started his own laboratory in 2013, he has combined experimental, computational, and theoretical approaches to uncover the mechanisms of molecular machineries that produce forces in the cell, with a particular focus on the actin cytoskeleton and endocytosis.
Michael M. Lacy, Yale University
Michael M. Lacy, Ph.D., completed his dissertation research in the laboratory of Prof. Julien Berro at Yale University. He earned his B.S. degree in Biochemistry at Tufts University in 2012 and his Ph.D. in Molecular Biophysics and Biochemistry at Yale in 2018, and he is now a postdoctoral researcher in the Berro laboratory before he leaves to launch his career in scientific editing and communication. Mike began the first stage of his Ph.D. research in the laboratory of Prof. Elizabeth Rhoades where he studied intrinsically disordered proteins. Mike's research in the Berro laboratory has developed and used single-molecule fluorescence microscopy to study membrane remodeling, focusing on the actin cytoskeleton and endocytosis in yeast. Mike was an editor for the Yale Journal of Biology and Medicine from 2014 to 2018, and he has been a member of the Biophysical Society since 2013. In his spare time, he enjoys bicycling, playing softball, and homebrewing beer.
Contents
1. Introduction to Clathrin-Mediated Endocytosis
2. Collecting Quantitative Data
3. From Raw Images to Quantitative Measurements: Extracting, Correcting, and Aligning the Fluorescence Microscopy Data
4. Using Quantitative Microscopy Data to Infer the Molecular Mechanisms of Endocytosis
5. Perspectives and Future of Quantitative Biology of Endocytosis
References
Author Biographies